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About liver disease


GENFIT is a biopharmaceutical company focused on discovering and developing drug candidates and diagnostic solutions targeting liver diseases, in particular those of metabolic origin, and hepatobiliary diseases, where there is still considerable unmet need.

Understanding patient needs

Conscious of the importance of strategically aligning our company with patient needs, our R&D efforts are focused on contributing to bringing new medicines to market for patients with serious diseases whose treatment options are limited or non-existent.

Our rigorous drug discovery and development process, and our commitment to improving health through innovation, have resulted in the creation of a pipeline dedicated to areas where we can lead and make a significant impact.

Our lead pipeline product elafibranor (GFT505) has recently completed a positive Phase 2b study in NASH (Non-Alcoholic Steato-Hepatitis) and is currently being evaluated in the Phase 3 study RESOLVE-IT. This metabolism-related liver disease, which can progress to cirrhosis and even liver cancer, shows a dramatically increasing prevalence worldwide. Elafibranor represents a major hope for patients and their physicians, who currently have no efficient treatment for NASH.

In addition to elafibranor, our R&D pipeline relies mainly on our world-renowned scientific expertise in gene regulation and nuclear receptors.
It is comprised of multiple drug candidate research programs targeting novel mechanisms of action including the inhibition of RORγ-t.

As we strongly believe that therapies and diagnostics are interrelated and mutually supportive, our efforts are also committed to identifying and validating new biomarkers, with a particular focus on NASH.

To better answer health challenges

The scientific results obtained over the past years, and an environment of health challenges with promising markets, strengthen GENFIT in its major decisions.
Our rock-solid intellectual property framework remains the guarantee for the company’s value creation, and supports our strategic position and growth.

We are proud to be a company making patients a priority, and as a public corporation, we always strive to provide our shareholders and partners with a return that reflects an outstanding performance and rewards for those who invest in our Company.

Corporate information
  • Corporate presentation
    November 2018
Press releases
  • GENFIT: Positive Phase 2 Results from Study of Elafibranor in Primary Biliary Cholangitis
  • GENFIT: Launch of a U.S. Phase 2 investigator-initiated study with nitazoxanide in patients with NASH-induced fibrosis
  • GENFIT announces plans to conduct registered Public Offering in the United States
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