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About liver disease

Scientific Advisory Board

The Scientific Advisory Board assists the Company in its strategic choices in the scientific and technical fields. The Scientific Advisory Board’s main missions are to advise the general management and scientific board of the Company in identifying strategies and selecting drug candidates, based, in particular, on the scientific results obtained by the Company (new targets, new compounds).

GENFIT’s Scientific Advisory Board is made up of six members who are internationally-recognized key opinion leaders in the field of of metabolic and inflammatory diseases, with a particular focus on the liver and gastroenterology. The Scientific Advisory Board is chaired by Professor Bart Staels, Co-founder of GENFIT.

Professeur Bart Staels

Co-founder of GENFIT, Chairman of the Scientific Advisory Board

Bart Staels has a PhD in Pharmacology from the University of Leuven in Belgium, and is a Professor at the University of Lille II in France and a Professor (“full Professor”) at the Faculty of Pharmacy, also at the University of Lille II. He is currently Director of the Inserm Unit UMR 1011 (A+ assessment from AERES, the French agency evaluating research and higher education institutions, and No.1 at the CSS4 Inserm), located in on the Institut Pasteur campus in Lille. Throughout his career, his research has primarily focused on the molecular pharmacology of cardiovascular and metabolic diseases. In particular, he has studied the role of nuclear receptors in controlling inflammation, metabolism, lipids and glucose homeostasis as well as the transcription mechanisms involved. Bart Staels is a member of several learned societies such as the European Atherosclerosis Society (EAS), the International Atherosclerosis Society (IAS) as a distinguished member, the New French Atherosclerosis Society (NSFA), the French Diabetes Society (SFD), the American Heart Association (AHA) (Premium Professional Silver Heart Member), the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).

He was awarded the Young Investigator prize by the EAS, the bronze medal by the CNRS (National Scientific Research Center), the Lifetime Achievement Award by the British Atherosclerosis Society, the Barré pharmaceutical prize in 1997 by the Faculty of Pharmacy of Montreal, as well as the JP Binet prize by the French Foundation of Medical Research, Paris, in 2011. He was also awarded the 2012 prize for “Distinguished Leader in Insulin Resistance” by the International Committee for Insulin Resistance (ICIR), presented during the 10th Annual World Congress of “Insulin Resistance, Diabetes & CVD” (WCIRDC) in Los Angeles, CA, in November 2012.

He is the author of more than 790 publications and has also written over 200 review articles.

Professeur Vlad Ratziu

Member of the Scientific Advisory Board

Professor of Medicine at the Pierre and Marie Curie University in Paris, he performs his hospital work at the La Pitié Salpetrière Hospital. His activity as a hepatologist, in particular in the field of NASH, made him one of the European leaders in this field.

Professeur Michael Trauner

Member of the Scientific Advisory Board

Professor of Medicine and consultant at the University academic hospital of Graz (Austria). He is a specialist in gastroenterology and hepatology. He is internationally recognized for his work in the field of hepatobiliary diseases (PBC, PSC).

Professeur Scott Friedman

Member of the Scientific Advisory Board

Professor of medicine and pharmacology, he is the Chief of the Division of Liver Diseases and Director of the Liver Research Laboratory at the Mount Sinai School of Medicine in New York. His work in the field of fibrosis associated with chronic liver diseases is internationally recognized.

He is the assistant editor-in-chief of the Hepatology review and is on the editorial board of the Journal of Gastroenterolgy and Hepatology.

Professeur Arun Sanyal

Member of the Scientific Advisory Board

Doctor Arun Sanyal is a Professor of Medicine and Director of the Division of Gastroenterology at the Medical Center of the Virginia Commonwealth University in Richmond, USA. Former President of the AASLD (American Association for the Study of Liver Diseases), Professor Arun Sanyal is considered as one of the greatest specialists in the diagnosis and treatment of NASH.

Professeur Jean-Frédéric Colombel

Member of the Scientific Advisory Board

Professor Jean-Frédéric Colombel is a gastroenterologist and currently the head of the Center of Inflammatory Diseases of the Intestine at the Department of Gastroenterology of Icahn School of Medicine at Mount Sinai in New York. Member of the learned society IOIBD (International Organization of Inflammatory Bowel Disease) since 2009, and scientific adviser to the AGA (American Gastroenterological Association) since 2006, he has also been chairman of several international organizations, including the ECCO (European Crohn’s and Colitis Organization).